1. He'd tell Wyatt that there's not much that thee thing can do once Okota's cut off from it, probably. They're all human and they have their own god and bullshit magical powers to cure people if they need to.

2. House will suggest she turns into something tastier than a big cat. Make yourself a cow, Okota. He'll polish up the cleaver. House will not actually want to kill her, but he'll be dramatic right back at her.